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EGFR Mouse Monoclonal Antibody(M6) |
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Catalog |
XHY162M |
XHY162L |
Quantity |
50µL |
100µL |
For research use only.
Application: WB
Species Cross-Reactivity: H
Molecular Weight: 170KD
Isotype: IgG1
Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Store : -20°C. Do not aliquot the antibody.
Recommended dilutions: WB: 1:1,000-3,000
Optimal dilutions should be determined by the end user.
Specificity: Antibody can detects endogenous EGFR protein.
Background: The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface
receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands.
Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG
and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and
autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits
adapter proteins like GRB2 which in turn activates complex downstream signaling cascades.
Applications:WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation
ChIP-Chormatin Immunoprecipitation
Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep