For research use only.

Application: WB

Species Cross-Reactivity: H, R, M   

Molecular Weight: 46KD    

Isotype: IgG1

Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Store : -20°C. Do not aliquot the antibody.

Recommended dilutions: WB: 1:1,000 -3,000

Optimal dilutions should be determined by the end user.

Specificity: Antibody can detects endogenous Cytokeratin 18 protein.. 

Background: Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the

most commonly found products of the intermediate filament gene family. They are expressed in single layer

epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript

variants encoding the same protein have been found for this gene.Keratin 18 is often used together with

keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that

enumerate circulating tumor cells in blood.

Applications:WB-Western blot   IHC-Immunochemistry   IF-Immunofluorescence   IP-Immunoprecipitation

                         ChIP-Chormatin Immunoprecipitation

Reactivity:   H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep