For research use only.

Application: WB  

Species Cross-Reactivity: H,  

Molecular Weight: 385-58KD         

Isotype: IgG1

Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Store : -20°C. Do not aliquot the antibody.

Recommended dilutions: WB: 1:3,000

Optimal dilutions should be determined by the end user.

Specificity: CA IX Mouse Monoclonal antibody detects endogenous CA IX proteins 

Background: The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that

catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa),

a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of

the best cellular biomarkers of hypoxia. Furthermore, recent studies examining the association between CAIX

levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable

prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of

hypoxic regions in many solid tumors .

Applications:WB-Western blot   IHC-Immunochemistry   IF-Immunofluorescence   IP-Immunoprecipitation

                          ChIP-Chormatin Immunoprecipitation

Reactivity:   H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep