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NSE Mouse Monoclonal Antibody(13E2) |
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Catalog |
XHY089M |
XHY089L |
Quantity |
50µL |
100µL |
For research use only.
Applications: WB,IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: ~47KD
Isotype: IgG1
Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Store : -20°C. Do not aliquot the antibody.
Recommended dilutions: WB: 1:2,000 IHC: 1:200
Optimal dilutions should be determined by the end user.
Specificity: The NSE Mouse Monoclonal antibody detects endogenous NSE proteins.
Background: Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate
and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits
(alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle.
The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE
(neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include
pediatric neuroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is
common in neuroendocrine neoplasms
Applications:WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation
ChIP-Chormatin Immunoprecipitation
Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep