|
CD68 Mouse Monoclonal Antibody(6F3) |
||
Catalog |
XHY073M |
XHY073L |
Quantity |
50µL |
100µL |
For research use only.
Applications: IHC
Species Cross-Reactivity: H, M, R
Molecular Weight: ~37KD
Isotype: IgG1
Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Store : -20°C. Do not aliquot the antibody.
Recommended dilutions: IHC: 1:200
Optimal dilutions should be determined by the end user.
Specificity: The CD68 antibody detects endogenous CD68 proteins
Background: The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated
to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and
at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in
intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue-
and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid
recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to
crawl over selectin bearing substrates or other cells.
Applications:WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation
ChIP-Chormatin Immunoprecipitation
Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep